Los Angeles: New release “Mission Impossible: Rogue Nation” cruised to the head of the box office, beating out fellow debut “Vacation” for top honors, according to industry estimates Sunday.

The fifth installment of the Blockbuster franchise stars Hollywood heavyweight Tom Cruise as a top-secret agent battling a rogue global organization that is trying to destroy the International Monetary Fund.

The action-thriller raked in $56 million in its inaugural weekend, according to box office tracker Exhibitor Relations.

In second place was the comedy misadventure “Vacation,” starring Ed Helms, Christina Applegate and comedy veteran Chevy Chase about a family holiday gone awry.

The debut came in far behind the top flick with $14.9 million.

Last week´s first-placed film, Marvel action flick “Ant-Man” starring Paul Rudd as a superhero, fell to third with $12.6 million after three weeks in theaters.

In fourth was animated comedy “Minions,” featuring three yellow mischief-making creatures from the film´s first installment “Despicable Me,” bringing in $12.2 million.

Not far behind was fellow animated film “Pixels,” about aliens who attack Earth after intercepting video games, earning $10.4 million.

Amy Schumer´s racy comedy “Trainwreck,” directed by Judd Apatow, about a boozy commitment-phobe who´s finally pinned down by a smitten doctor, fell to sixth place with $9.7 million.

In seventh was “Southpaw,” starring Jake Gyllenhaal as a boxer at the end of his bruising career, which brought in $7.5 million.

The number eight spot went to drama-mystery “Paper Towns” about a road trip to find a missing girl next door, with $4.6 in ticket sales.

The Disney animated flick “Inside Out” slid to ninth, netting $4.5 million its seventh week in North American cinemas.

Rounding out the top ten was the ever-popular dinosaur Blockbuster “Jurassic World,” which raked in $3.8 million.

The dino thriller has become the third biggest global hit of all times, according to Exhibitor Relations.

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